Foxm1 in cancer
WebOct 25, 2024 · In esophageal cancer, FOXM1 has been related to cell growth, proliferation, and metastasis [49,61,62] and plays a key role in both PTX resistance in breast cancer and ovarian cancer . Wang et al. reported that UA inhibits the proliferation of breast cancer cells by suppressing the expression of FOXM1 . Therefore, it can be hypothesized that UA ... WebApr 13, 2024 · In research published in The Journal of Clinical Investigation and in Breast Cancer Research and Treatment, Benita and John describe a new inhibitory compound that blocks the Forkhead box protein M1 (FOXM1), a protein that plays a critical role in tumor cell growth and metastasis.
Foxm1 in cancer
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WebAug 17, 2024 · Our findings highlight the immunoregulatory role of FOXM1 in cancer cells, suggesting the need for future investigations exploring FOXM1 as a prognostic … WebExpression and functional characterization of FOXM1 in non-small cell lung cancer Yan Zhang, Wen-bin Qiao, Li Shan Department of Thoracic Oncology, Tumor Hospital …
WebJun 21, 2024 · FOXM1 expression is elevated in small cell lung cancer cells in vitro and in vivo. While FOXM1 regulates cell proliferation and is correlated to many cancer types, … WebJun 19, 2024 · As a master transcriptional regulator, FOXM1 promotes critical oncogenic phenotypes in ovarian cancer, including: (1) cell proliferation, (2) invasion and metastasis, (3) chemotherapy resistance, (4) cancer stem cell (CSC) properties, (5) … National Center for Biotechnology Information
WebAug 17, 2024 · PMID: 35975458 FOXM1 Inhibition Enhances the Therapeutic Outcome of Lung Cancer Immunotherapy by Modulating PD‐L1 Expression and Cell Proliferation Hamadi Madhi,1 ,2 Jeon‐Soo Lee,1 Young Eun Choi,1 Yan Li,1 Myoung Hee Kim,2 Yongdoo Choi,1 and Sung‐Ho Goh1 Hamadi Madhi 1 Research Institute, National … WebOverexpression of FOXM1 has been reported in more than 20 types of human cancer. In recent years, FOXM1 has been implicated in diverse cellular processes and also a …
WebMay 1, 2024 · FOXM1 promoted the tumorigenesis of CRC in vitro To explore the effects of FOXM1 on CRC progression in vitro, we obtained FOXM1 upregulating and downregulating cells for our subsequent experiments in vitro.
WebApr 10, 2024 · Accumulating evidence has implicated a pivotal role for FOXO3, FOXM1 and SIRT6 in cancer progression. The majority of researches focused on the functi… psh poplar church roadWebFeb 29, 2012 · In this study, we examined whether FOXM1 plays a role in cell death induced by DNA-damage in human tumor cell lines with mutant p53. We demonstrate that stable … horsea 58/97WebCircRNA ZNF609 Knockdown Represses the Development of Non-Small Cell Lung Cancer via miR-623/FOXM1 Axis Javascript is currently disabled in your browser. Several features of this site will not function whilst javascript is disabled. psh porcWebApr 3, 2006 · Abstract. The transcription factor Forkhead box M1 (FoxM1) is overexpressed in malignant glioma. However, the functional importance of this factor in human glioma is not known. In the present study, we found that FoxM1B was the predominant FoxM1 isoform expressed in human glioma but not in normal brain tissue. The level of FoxM1 protein … horsea best movesetWebNov 14, 2012 · FoxM1 is a key protein controlling the G 1 to S and G 2 to M checkpoints; thus, it will be interesting to determine the role of miRNA in the regulation of FoxM1 during the maturation of cancer stem cells. Furthermore, it will be interesting to determine whether the same miRNAs modulate the function of FoxM1 and Wnt/β-catenin signaling, hence ... psh plaiWebGiven that FOXM1 is known to be involved in endocrine resistance, expansion of stem-like cancer cells, stem cell self-renew, cancer initiation and metastasis, it is conceivable that … horsea bdspWebFeb 15, 2010 · FoxM1 was over-expressed in hepatocellular carcinoma samples compared to adjacent non-hepatocellular carcinoma liver samples. FoxM1 siRNA was successfully transfected into MHCC-97H cells,... horsea bdsp location