Web25 mei 2024 · 9582 Background: The phase III KEYNOTE-189 study (NCT02578680), showed significant improvements in OS and PFS with pembro + chemo vs placebo + chemo in pts with previously untreated metastatic nonsquamous NSCLC without sensitizing EGFR/ALK mutations. We report the protocol-specified final analysis of KEYNOTE-189. … WebEven his tumor alone is an unlikely cause of his SIADH, because he did not develop hyponatremia until after his tumor biopsy, and hyponatremia did not recur after hypertonic saline was discontinued. Conclusions NSCLC as a cause of SIADH is extremely rare.
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Web12 dec. 2024 · metastatic NSCLC in KRYSTAL-1 [see Clinical Studies (14)]. Patients received adagrasib 600 mg orally twice daily (n = 116). Among patients who received adagrasib, 45% were exposed for 6 months or longer and 4% were exposed for greater than one year. The median age of patients who received adagrasib was 64 years (range 25 to … Web28 apr. 2024 · This discussion will present the clinical manifestations of non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). Screening and risk factors for lung cancer, as well as an overview of the initial evaluation, diagnosis, treatment, and prognosis of lung cancer are presented separately. michael m hensley art
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Web30 jan. 2024 · 13. Greenblatt HK, Greenblatt DJ. Antidepressant-associated hyponatremia in the elderly. J Clin Psychopharmacol 2016; 36(6): 545–549. 14. Anpalahan M. Chronic idiopathic hyponatremia in older people due to syndrome of inappropriate antidiuretic hormone secretion (SIADH) possibly related to aging. J Am Geriatr Soc 2001; 49(6): … Web1 sep. 2024 · Labs revealed low sodium 117 mmol/L (137–145 mmol/L) and low chloride 85 mmol/L (98–107 mmol/L), but albumin was normal at 4.0 g/dL (3.5–5.0 g/dL). Serum … Web2 dagen geleden · During a Targeted Oncology™ Case-Based Roundtable™ event, Mohammadbagher Ziari, MD, discussed with participants how they approach later lines of therapy for patients with multiple myeloma. Mohammadbagher Ziari, MD. Assistant Clinical Professor. Department of Medical Oncology & Therapeutics Research. how to change mysql bind address