WebCommon side effects of tizanidine include dry mouth, sleepiness, weakness, and dizziness. [5] Serious side effects may include low blood pressure, liver problems, psychosis, and QT prolongation. [5] It is unclear if use in pregnancy and breastfeeding is safe. [6] It is an α2-adrenergic agonist, but how it works is not entirely clear. [5] WebThe common side effects of tizanidine include drowsiness, dizziness, hypotension, speech disturbances, and blurred vision. A baseline creatinine should be obtained as well as a baseline liver function. The liver function tests should be repeated at 1, 3, and 6 months and should be gradually tapered to discontinue use.
Tizanidine - Wikipedia
WebJun 3, 2024 · Tizanidine can have serious side effects in people whose kidneys are not functioning properly, as the body’s ability to clear the drug becomes greatly impaired and toxicity can develop quickly. Likewise, in people with liver problems, serious toxicity from tizanidine can develop rapidly. Web5.2 Risk of Liver Injury Tizanidine hydrochloride may cause hepatocellular liver injury. Tizanidine hydrochloride should be used with caution in patients with any hepatic impairment. Monitoring of aminotransferase levels is recommended for baseline and 1 month after maximum dose is achieved, or if hepatic injury is suspected. bauplan straße
Tizanidine - StatPearls - NCBI Bookshelf
WebTizanidine (Zanaflex) can damage the liver. Because of this, if you have liver problems, you shouldn't take this medication. If you are going to be taking tizanidine (Zanaflex) for a … WebJun 25, 2014 · More likely liver: Tizanidine more likely will cause damage to your liver due to the metabolism of the drug but its about 60 % excreted through the kidneys, so it's possible that it could cause some damage at very high doses, but it normally damages liver. Ibuprofen is more likely causing kidney issues. WebJun 1, 2024 · When you first start taking tizanidine, your doctor will give you a small dose. Your dose will then be increased at 3- to 4-day intervals until you are on a dose that suits … tina jago